Dr. Sneha J
Dr. Sneha S

MBBS, DGO, DNB (OBG), Fellowship in Reproductive Medicine

Consultant - IVF Specialist, Female Sexual Health & Gynaecology

Dr. Pramod Krishnappa
Dr. Pramod Krishnappa

MBBS, MS (Surg), DNB (Uro), ChM (Edinburgh), FECSM, Fellow Andrology (Spain)

Sr. Consultant Andrologist & Urologist

Egg Quality in Women

Blog Date - NU FertilityJanuary 12, 2026

Blog Date - NU FertilityNU Fertility

Blog Date - NU FertilityIVF

Egg Quality in Women

When pregnancy does not happen as expected, fertility testing often brings up the topic of egg quality. For many women, this is the first time they hear the term in detail. Egg quality is not something that can be felt or noticed in daily life, yet it plays a central role in conception and early pregnancy.

Doctors come across many women who appear medically well but struggle to conceive. In several of these cases, the issue lies not in the uterus or tubes, but in how the eggs are developing, and this becomes the starting point of treatment.

What Doctors Mean When They Talk About Egg Quality

Egg quality refers to how healthy an egg is at the time of ovulation and whether it can fertilise and develop normally. Eggs with stable genetic material are more likely to form healthy embryos and implant successfully.

Women are born with all the eggs they will ever have. Over time, these eggs age along with the body. This is a natural process, but it does not follow the same timeline for everyone. Two women of the same age can have very different fertility outcomes.

Egg quality cannot be measured directly. Doctors rely on test results, ultrasound findings, and how the ovaries respond during treatment to understand what may be happening.

Why Egg Quality Can Decline

There is usually no single cause behind poor egg quality. Most often, it is a combination of factors.

Age plays a role. Sometimes a big one. As women grow older, eggs are more likely to carry chromosomal changes. This can affect fertilisation or lead to early pregnancy loss.

Hormonal imbalances may also interfere with egg development. Hormonal imbalances can lead to issues like thyroid disorders, irregular ovulation, and other endocrine conditions, all of which can disrupt how eggs mature.

Medical conditions such as polycystic ovary syndrome and endometriosis are commonly linked with fertility concerns. Not every woman with these conditions will have poor egg quality, but they can influence ovarian function over time.

Lifestyle factors matter more than many realise. Smoking, alcohol intake, long-term stress, lack of sleep, and nutritional deficiencies can affect egg health. Women who have undergone chemotherapy, radiation therapy, or ovarian surgery may also experience changes.

 

Are There Any Symptoms?

Poor egg quality does not usually cause pain or visible symptoms. Many women discover it only during a fertility evaluation.

Doctors may suggest further testing if there is:

  • Difficulty conceiving despite regular cycles

  • Repeated early miscarriages

  • Irregular or unpredictable periods

  • Limited response to fertility medications

  • IVF cycles with low fertilisation or weak embryo development

These signs do not confirm a diagnosis on their own. They simply point toward the need for closer assessment.

How Egg Quality Is Assessed

At NU Fertility, evaluation begins with conversation, not tests. Doctors take time to understand menstrual patterns, lifestyle habits, previous pregnancies, and any past fertility treatment.

Blood tests such as AMH, FSH, and estradiol are commonly used to assess ovarian function. A pelvic ultrasound helps estimate ovarian reserve by counting resting follicles.

In many cases, the clearest information comes during treatment itself. The number of eggs retrieved, how they fertilise, and how embryos grow often reveal more than tests alone.

Standard Tests Used to Assess Egg Health and What They Indicate

Test or Assessment

What It Helps Doctors Understand

AMH (Anti-Müllerian Hormone)

Helps doctors estimate how actively the ovaries are functioning and roughly how many eggs may still be present. It does not tell whether the eggs are “good” or “bad,” but it gives useful background when deciding the next steps.

FSH (Follicle-Stimulating Hormone)

FSH is checked early in the cycle to see how the ovaries are responding. Higher values may indicate that more effort is needed to release an egg, so doctors interpret them in conjunction with age and cycle pattern.

Estradiol levels

It gives an early picture of ovarian activity in a cycle. The level helps doctors judge whether hormone signals are lining up as expected at that stage.

Antral follicle count

Shows the number of resting follicles in the ovaries, offering insight into ovarian activity and response potential.

Menstrual cycle pattern

Regularity, cycle length, and changes over time often provide practical clues about ovulation and egg maturity.

Response during treatment

How eggs grow, mature, and fertilise during treatment often gives the clearest picture of egg quality in real-world conditions.

Treatment Options for Poor Egg Quality in NU Bangalore

Egg quality does not improve in the sense of becoming “younger” again. Once it declines, treatment will use the available eggs most effectively.

The first step is usually to look at factors that can still be influenced. This may include:

  • Treating hormonal issues that interfere with regular ovulation

  • Advising changes in daily habits that affect reproductive health

  • Offering nutritional support where it is clinically relevant

Based on age, test findings, and overall fertility assessment, some women may be advised to try ovulation induction or intrauterine insemination before moving to advanced treatment.

When concerns about egg quality are more pronounced, IVF is commonly advised. IVF allows careful monitoring of egg growth, controlled fertilisation, and assessment of embryo development. It is essential to understand that even with fertility treatments like IVF, the outcome depends on several other factors as well, including laboratory standards and the experience of the doctors and the embryologists.

Factors That Can Affect Treatment When Egg Quality Is Reduced

Being told that egg quality is lower than expected does not mean treatment will not work. In everyday clinical practice, results depend on more than egg health alone. This is why women with similar reports can have very different outcomes over time.

So, for women hoping for egg quality treatment and to get pregnant, the treatment plan needs to consider the broader picture. Reproductive health is a complicated and varied subject, and a positive pregnancy test depends on more than one factor.

Some of the commonly considered factors include:

  • Age at the time of treatment
    Age still plays a role, even when test results look similar. Younger women often have better chances because eggs tend to have fewer genetic changes.

  • Hormonal balance
    Hormones guide egg development, ovulation, conception and even how the pregnancy will proceed. Hormonal imbalances can eventually affect treatment outcomes, even when the egg reserve appears reasonable.

  • Uterine health
    The condition of the uterus also matters. A thin uterine lining, or issues like fibroids or endometriosis, can all cause the pregnancy to not catch, even with a healthy embryo. For this reason, doctors usually look at uterine findings along with egg-related factors before planning further treatment.

  • Sperm health
    Conception depends on both partners. Fertilisation and early development are influenced by sperm health as much as by egg health.

  • Overall physical and lifestyle health
    Long-term stress, sleep patterns, nutrition, and untreated medical conditions can affect how the reproductive system functions and responds to treatment.

Because of these variations, treatment decisions are rarely based on a single test or report. Doctors adjust care based on how these factors interact, allowing treatment to be tailored to the individual rather than following a fixed approach.

Care at NU Hospitals when Egg Quality is Affected

At NU Hospitals, fertility concerns are reviewed along with the patient’s overall health. NU Fertility works with other departments when conditions such as thyroid problems, endometriosis, or hormonal disorders are present. This helps ensure that related medical issues are not missed while planning care.

Treatment decisions are based on test findings and clinical response over time. There is no fixed plan used for everyone. Doctors explain possible options clearly and discuss practical limitations where they exist. Evaluation and follow-up are supported by modern diagnostic tools, allowing treatment to be adjusted as needed. Patients can trust the evaluation process and follow-up care, which is supported by modern diagnostic tools and a compassionate care staff.

Frequently Asked Questions

  1. Can women with poor egg quality still get pregnant?
    Many women conceive with appropriate fertility treatment and medical guidance.
  1. Is poor egg quality the same as low egg count?
    Egg count refers to how many eggs remain, while egg quality refers to how healthy those eggs are.
  1. Does IVF guarantee success in poor egg quality cases?
    IVF improves the chances but does not guarantee pregnancy. Outcomes vary from person to person.
  1. At what age does egg quality decline?
    Egg quality generally begins to decline in the early 30s, with a more noticeable change after 35. This varies widely.
  1. Is donor egg IVF the first option?
    It is considered only when other treatment approaches are unlikely to succeed.
  1. When should a fertility specialist be consulted?
    Women above 35 trying for six months, or those with irregular cycles or repeated pregnancy loss, should seek evaluation early.
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